Results from this analysis show that conductivity transitions can be effectively mitigated without compromising process performance by optimizing the trade-off between wash buffer concentration and wash phase duration. Siemens chemistry analyzers are recognized for its efficiency, reliability and accuracy, ensuring an ideal solution for a number. Thank you for your interest in the Nova Biomedical BioProfile 400 Analyzer (ID : 20808). Pictures enclosed and the actual unit may vary unless specified. Prices do not include S/H unless otherwise indicated. They also come with our standard 6 Month parts and labor warranty. two BioProfile FLEX analyzers and two sets of reference analyzers (Nova BioProfile 400. Siemens is a leading global provider and manufacturer of various equipment for the automotive, chemicals, food, beverage, healthcare, oil, gas, pharmaceutical, and other industries. Typical turnaround for refurbishing of used lab equipment is 2-4 weeks. A potentiometric electrode selective for sodium ions was used to measure effluent counterion concentrations from two preparative resins during high pH washes, and the number of exchangeable counterions was compared to predictions made using ion exchange equilibrium theory. An integrated multi-functional off-line analyzer, the BioP. Further investigation revealed that wash buffer concentration, resin ligand density, and resin ligand pK have a profound effect on the magnitude of the conductivity transitions and the shape of corresponding pH traces. In some cases, the absolute conductivity change was greater than 6 mS/cm which was sufficient to affect target protein retention on the column. These conductivity transitions resulted in a conductivity drop during pH increase and a conductivity rise during pH decrease. Large conductivity fluctuations were observed during a high pH wash step in a weak cation exchange chromatography process. Nova Medical BioProfile 400 Analyzer, s/n: T08203050, 100-240v, 0.6-1.3 amps 45 Nova Medical BioProfile 400 Analyzer, s/n: T08203050, 100-240v, 0.6-1. At 72 h, the culture medium was filtered and the indicated substrates and metabolites quantitated using a Nova Bioprofile 400 analyzer.